Impact of 3D Imaging on Translational Research
Small Animal Imaging has been transformed by 3D imaging techniques, which provide volumetric visualization of organs, tumors, and tissues in preclinical models. 3D imaging enables a more accurate assessment of anatomical structures and pathological changes, supporting translational research efforts.
Techniques like micro-CT, MRI, and optical tomography offer detailed 3D reconstructions, allowing researchers to quantify tumor volume, organ size, and vascular networks with precision. These volumetric datasets improve the evaluation of therapeutic interventions, revealing subtle changes that 2D imaging may miss.
3D imaging also enhances the integration of computational modeling and AI-based analysis, providing quantitative insights that guide preclinical decision-making. Longitudinal 3D imaging allows repeated measurements in the same animal, reducing variability and the number of animals required for studies.
By offering detailed anatomical and functional information, 3D imaging accelerates translational research, bridging the gap between preclinical findings and clinical applications, ultimately improving drug development and disease modeling.